Danish Genetically Modified Animal Resource

Genetically modified animals are an essential tool to explore molecular mechanisms in the body and for innovating therapeutic and diagnostic strategies to combat disease. The national core facility DAGMAR produces cutting-edge transgenic animal models in zebrafish, mice and pigs to collaborating research environments across the country.

The unification of the described resources in a single infrastructure will enable collaborating academic and industrial researchers to study far more aspects of gene function than has previously been possible using a single species. Because no animal model is ideal for studying all aspects of gene function, we envision that the flexibility to choose the most suitable animal system for each biological question will greatly speed up bench-to-bedside research: from initial screening of gene function through understanding of the involved molecular mechanisms to innovation and testing of novel therapeutic strategies in preclinical studies.

The production facility is mainly located at the University of Aarhus with essential contributions from the University of Copenhagen. It is the only national source of transgenic zebrafish and minipigs, and the only facility providing transgenic mice nationwide.

DAGMAR was made possible by a 30 mio DKK grant from the Danish National Research Infrastructures Programme.